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1

Denoising of PET images by combining wavelets and curvelets for improved preservation of resolution and quantitation

Le Pogam, A., Hanzouli, H., Hatt, M., Cheze Le Rest, C., Visvikis, D.

Journal:

Medical Image Analysis

Year:

2013

Language:

english

File:

PDF, 2.57 MB

english, 2013

2

The PRESLO study: evaluation of a global secondary low back pain prevention program for health care personnel in a hospital setting. Multicenter, randomized intervention trial

Angélique Denis, Amélie Zelmar, Marie-Annick Le Pogam…

Journal:

BMC Musculoskeletal Disorders

Year:

2012

Language:

english

File:

PDF, 283 KB

english, 2012

3

3D modeling and characterization of the human CD115 monoclonal antibody H27K15 epitope and design of a chimeric CD115 target

Grellier, Benoît, Grellier, Benoît, Le Pogam, Fabrice, Le Pogam, Fabrice, Vitorino, Marc, Vitorino, Marc, Starck, Jean-Philippe, Starck, Jean-Philippe, Geist, Michel, Geist, Michel, Duong, Vanessa, Du

Journal:

Year:

2014

Language:

english

File:

PDF, 3.88 MB

english, 2014

4

Competing English, Spanish, and French alabaster trade in Europe over five centuries as evidenced by isotope fingerprinting

Kloppmann, W., Leroux, L., Bromblet, P., Le Pogam, P.-Y., Cooper, A. H., Worley, N., Guerrot, C., Montech, A. T., Gallas, A. M., Aillaud, R.

Journal:

Proceedings of the National Academy of Sciences

Year:

2017

Language:

english

File:

PDF, 1.30 MB

english, 2017

5

Untargeted metabolomics reveal lipid alterations upon 2-deoxyglucose treatment in human HaCaT keratinocytes

Le Pogam, Pierre, Doué, Mickaël, Le Page, Yann, Habauzit, Denis, Zhadobov, Maxim, Sauleau, Ronan, Le Dréan, Yves, Rondeau, David

Journal:

Journal of Proteome Research

Year:

2018

Language:

english

File:

PDF, 1.63 MB

english, 2018

6

La performance hospitalière : à la recherche d'un modèle multidimensionnel cohérent

Le Pogam, Marie Annick, Luangsay-Catelin, Carine, Notebaert, Jean-François

Journal:

Management & Avenir

Year:

2009

File:

PDF, 563 KB

2009

7

Secondary metabolites from lichen as potent inhibitors of advanced glycation end products and vasodilative agents

Schinkovitz, Andreas, Le Pogam, Pierre, Derbré, Séverine, Roy-Vessieres, Emilie, Blanchard, Patricia, Thirumaran, Sangeetha-Laura, Breard, Dimitri, Aumond, Marie-Chistine, Zehl, Martin, Urban, Ernst,

Journal:

Year:

2018

Language:

english

File:

PDF, 1.25 MB

english, 2018

8

Î±-Glucosidase Inhibitory Depsidones from the Lichen Parmotrema tsavoense

Duong, Thuc-Huy, Hang, Tai-Xuan-Hoa, Pogam, Pierre Le, Tran, Thanh-Nha, Mac, Dinh-Hung, Dinh, Minh-Hiep, Sichaem, Jirapast

Journal:

Year:

2020

File:

PDF, 176 KB

2020

9

Design, synthesis, and antiviral properties of 4′-substituted ribonucleosides as inhibitors of hepatitis C virus replication: The discovery of R1479

David B. Smith, Joseph A. Martin, Klaus Klumpp, Stewart J. Baker, Peter A. Blomgren, Rene Devos, Caroline Granycome, Julie Hang, Christopher J. Hobbs, Wen-Rong Jiang, Carl Laxton, Sophie Le Pogam, Vin

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2007

Language:

english

File:

PDF, 174 KB

english, 2007

10

The application of phosphoramidate ProTide technology to the potent anti-HCV compound 4′-azidocytidine (R1479)

Christopher McGuigan, Mary Rose Kelleher, Plinio Perrone, Sinead Mulready, Giovanna Luoni, Felice Daverio, Sonal Rajyaguru, Sophie Le Pogam, Isabel Najera, Joseph A. Martin, Klaus Klumpp, David B. Smi

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2009

Language:

english

File:

PDF, 288 KB

english, 2009

11

Non-nucleoside inhibitors of HCV NS5B polymerase. Part 1: Synthetic and computational exploration of the binding modes of benzothiadiazine and 1,4-benzothiazine HCV NS5b polymerase inhibitors

Robert T. Hendricks, Jay B. Fell, James F. Blake, John P. Fischer, John E. Robinson, Stacey R. Spencer, Peter J. Stengel, April L. Bernacki, Vincent J.P. Leveque, Sophie Le Pogam, Sonal Rajyaguru, Isa

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2009

Language:

english

File:

PDF, 1.25 MB

english, 2009

12

Cyclic amide bioisosterism: Strategic application to the design and synthesis of HCV NS5B polymerase inhibitors

Hanbiao Yang, Robert T. Hendricks, Nidhi Arora, Dov Nitzan, Calvin Yee, Matthew C. Lucas, Yanli Yang, Amy Fung, Sonal Rajyaguru, Seth F. Harris, Vincent J.P. Leveque, Julie Q. Hang, Sophie Le Pogam, D

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2010

Language:

english

File:

PDF, 653 KB

english, 2010

13

Séparation chromatographique d'acides aminés phosphoniques N-substitués

J. Le Pogam, H. Jensen, E. Neuzil

Journal:

Journal of Chromatography A

Year:

1973

File:

PDF, 447 KB

1973

14

C035 DNA vaccination as immunotherapy adjuvant in MDS

R. Padua, C. Le Pogam, S. Beurlet, M. Reboul, P. Krief, R. West, M. Pla, D. Charron, C. Chomienne

Journal:

Leukemia Research

Year:

2009

Language:

english

File:

PDF, 40 KB

english, 2009

15

Séparation chromatographique de la ciliatine et de la phosphoéthanolamine

E Neuzil, H Jensen, J Le Pogam

Journal:

Journal of Chromatography A

Year:

1969

File:

PDF, 259 KB

1969

16

PML-RARA–targeted DNA vaccine induces protective immunity in a mouse model of leukemia

Padua, Rose Ann, Larghero, Jerome, Robin, Marie, Pogam, Carol le, Schlageter, Marie-Helene, Muszlak, Sacha, Fric, Jan, West, Robert, Rousselot, Philippe, Phan, Thi Hai

Journal:

Nature Medicine

Year:

2003

Language:

english

File:

PDF, 401 KB

english, 2003

17

Existence of hepatitis C virus NS5B variants naturally resistant to non-nucleoside, but not to nucleoside, polymerase inhibitors among untreated patients

Le Pogam, S., Seshaadri, A., Kosaka, A., Chiu, S., Kang, H., Hu, S., Rajyaguru, S., Symons, J., Cammack, N., Najera, I.

Journal:

Journal of Antimicrobial Chemotherapy

Year:

2008

Language:

english

File:

PDF, 356 KB

english, 2008

18

2'-Deoxy-4'-azido Nucleoside Analogs Are Highly Potent Inhibitors of Hepatitis C Virus Replication Despite the Lack of 2'- -Hydroxyl Groups

Klumpp, K., Kalayanov, G., Ma, H., Le Pogam, S., Leveque, V., Jiang, W.-R., Inocencio, N., De Witte, A., Rajyaguru, S., Tai, E.

Journal:

Journal of Biological Chemistry

Year:

2007

Language:

english

File:

PDF, 305 KB

english, 2007

19

Design and Characterization of R1626, A Prodrug of the HCV Replication Inhibitor R1479 (4′-Azidocytidine) With Enhanced Oral Bioavailability

Klaus Klumpp, David Smith, Michael Brandl, Tom Alfredson, Keshab Sarma, Mark Smith, Isabel Najera, Wen-Rong Jiang, Sophie Le Pogam, Vincent Leveque, Han Ma, Yaping Tu, Rebecca Chan, Chiao-Wen Chen, Xi

Journal:

Antiviral Research

Year:

2007

Language:

english

File:

PDF, 65 KB

english, 2007

20

Novel 4′-Azido-2′-Deoxy-Nucleoside Analogs are Potent Inhibitors of NS5B-Dependent HCV Replication

David Smith, Han Ma, Sophie Le Pogam, Vincent Leveque, Carl Brown, Nils Gunnar Johansson, Genadiy Kalayanov, Staffan Eriksson, Elena Usova, Christian Sund, Anna Winqist, Tatiana Maltseva, Mark Smith,

Journal:

Antiviral Research

Year:

2007

Language:

english

File:

PDF, 68 KB

english, 2007

21

Évaluation des ratios normalisés de mortalité hospitalière à partir des données du programme de médicalisation des systèmes d’information (PMSI) : comparaison de modèles d’ajustement

Y. Lefebvre, S. Gomez, F. Mégas, A. Patris, C. Colin, M.-A. Le Pogam

Journal:

Revue d'Épidémiologie et de Santé Publique

Year:

2012

Language:

french

File:

PDF, 64 KB

french, 2012

22

Développement d’indicateurs de management des ressources humaines et de sécurité des patients hospitalisés, France

C. Colin, M.-A. Le Pogam, C. Paillé, L. Moret, S. Tricaud-Vialle, P. Michel

Journal:

Revue d'Épidémiologie et de Santé Publique

Year:

2012

Language:

french

File:

PDF, 60 KB

french, 2012

23

Développement d’indicateurs de sécurité des patients hospitalisés à partir des bases de données médico-administratives hospitalières : le projet PSI-CLARTE, France

M.-A. Le Pogam, F. Chollet, F. Goutille, A. Bestion, S. Couray-Targe, C. Colin

Journal:

Revue d'Épidémiologie et de Santé Publique

Year:

2012

Language:

french

File:

PDF, 63 KB

french, 2012

24

In vitro selected Con1 subgenomic replicons resistant to 2′-C-Methyl-Cytidine or to R1479 show lack of cross resistance

Sophie Le Pogam, Wen-Rong Jiang, Vincent Leveque, Sonal Rajyaguru, Han Ma, Hyunsoon Kang, Sharon Jiang, Margaret Singer, Samir Ali, Klaus Klumpp, Dave Smith, Julian Symons, Nick Cammack, Isabel Nájera

Journal:

Year:

2006

Language:

english

File:

PDF, 275 KB

english, 2006

25

Imagerie moléculaire de la maladie de Parkinson : données actuelles

J.-L. Baulieu, A. Le-Pogam, A. Leborgne, D. Guilloteau, C. Prunier-Aesch

Journal:

Médecine Nucléaire

Year:

2008

Language:

french

File:

PDF, 146 KB

french, 2008

26

Imagerie moléculaire du transporteur vésiculaire de l’acétylcholine (VACh) par le [123I]-5-iodobenzovézamicol dans la démence de type Alzheimer (DTA)

F. Quetu, C. Prunier, Le Pogam, C. Hommet, G. Tamagnan, M. Allard, D. Guilloteau, J. Seibyl, J.L. Baulieu

Journal:

Médecine Nucléaire

Year:

2009

File:

PDF, 783 KB

2009

27

[499] NOVEL 4-AZIDO-2-DEOXY-NUCLEOSIDE ANALOGS ARE POTENT INHIBITORS OF NS5B-DEPENDENT HCV REPLICATION

D.B. Smith, H. Ma, S. Le Pogam, V. Leveque, C. Brown, N.G. Johansson, G. Kalayanov, S. Eriksson, E. Usova, C. Sund, A. Winqvist, T. Maltseva, M. Smith, W.R. Jiang, N. Cammack, J.A. Martin, I. Najera,

Journal:

Journal of Hepatology

Year:

2007

Language:

english

File:

PDF, 138 KB

english, 2007

28

[622] R1479, A NOVEL HEPATITIS C POLYMERASE INHIBITOR: LACK OF PRE-EXISTING RESISTANCE MUTATION SUPPORTS THE OBSERVED IN VIVO HIGH BARRIER TO RESISTANCE

S. Le Pogam, A. Kosaka, S. Hu, H. Kang, A. Seshaadri, J. Symons, K. Klumpp, N. Cammack, I. Najera

Journal:

Journal of Hepatology

Year:

2007

Language:

english

File:

PDF, 149 KB

english, 2007

29

[602] INHIBITION OF HCV REPLICATION BY PSI-6130: CHARACTERIZATION OF ACTIVITY IN THE HCV REPLICON SYSTEM

W.R. Jiang, S. Ali, S. Le Pogam, C. Daniel, S. Chiu, T. Kretz, I. Najera, P. Furman, N. Cammack, J. Symons

Journal:

Journal of Hepatology

Year:

2007

Language:

english

File:

PDF, 149 KB

english, 2007

30

21 LOW LEVEL OF RESISTANCE, LOW VIRAL FITNESS AND ABSENCE OF RESISTANCE MUTATIONS IN BASELINE QUASISPECIES MAY CONTRIBUTE TO HIGH BARRIER TO R1626 RESISTANCE IN VIVO

S. Le Pogam, A. Seshaadri, H. Kang, A. Kosaka, S. Hu, J. Symons, K. Klumpp, N. Cammack, I. Najera

Journal:

Journal of Hepatology

Year:

2008

Language:

english

File:

PDF, 60 KB

english, 2008

31

851 ANTIVIRAL POTENCY OF R1479, ACTIVE COMPOUND DERIVED IN VIVO FROM PRODRUG R1626, DEMONSTRATED ACROSS HCV GENOTYPES 1-6 IN NS5B RECOMBINANT ENZYMES AND HCV REPLICONS

V. Leveque, S. Le Pogam, H. Kang, G. Ao-Ieong, A. Kosaka, A. Seshaadri, J. Symons, N. Cammack, K. Klumpp, I. Najera

Journal:

Journal of Hepatology

Year:

2008

Language:

english

File:

PDF, 53 KB

english, 2008

32

958 NO EVIDENCE OF R7128 DRUG RESISTANCE AFTER UP TO 4 WEEKS TREATMENT OF GT 1, 2 AND 3 HEPATITIS C VIRUS INFECTED INDIVIDUALS

S. Le Pogam, A. Seshaadri, A. Kosaka, S. Hu, A. Beard, S. Julian, C. Nick, I. Najera

Journal:

Journal of Hepatology

Year:

2009

Language:

english

File:

PDF, 45 KB

english, 2009

33

62 ACTIVITY OF DANOPREVIR PLUS LOW-DOSE RITONAVIR (DNV/R) IN COMBINATION WITH PEGINTERFERON ALFA-2A (40KD) PLUS RIBAVIRIN (PEGIFNa-2A/RBV) IN PREVIOUS NULL RESPONDERS

R. Rouzier, D. Larrey, E.J. Gane, A. Wiercinska-Drapalo, L. Chang, Y. Zhang, B. Gujral, S. Le Pogam, I. Nájera, P. Smith, N. Shulman, J. Tran

Journal:

Journal of Hepatology

Year:

2011

Language:

english

File:

PDF, 45 KB

english, 2011

34

710 EVOLUTION OF GLOMERULAR FILTRATION RATE IN HIV-INFECTED, HIV-HBV COINFECTED AND HBV-INFECTED PATIENTS RECEIVING TENOFOVIR

L. Cotte, M.-A. Le Pogam, J.-B. Okon, P. Trolliet, C. Brochier, M. Maynard, F. Bailly, P. Miailhes, F. Zoulim

Journal:

Journal of Hepatology

Year:

2011

Language:

english

File:

PDF, 40 KB

english, 2011

35

130 Lack of association of meticillin-resistant Staphylococcus aureus and long term use of azithromycin in cystic fibrosis patients: a French cohort study

N. Sicot, M.A. Le Pogam, S. Durupt, R. Nove-Josserand, P. Reix, I. Durieu

Journal:

Journal of Cystic Fibrosis

Year:

2012

Language:

english

File:

PDF, 63 KB

english, 2012

36

Tracking the extramedullary PML-RARα-positive cell reservoirs in a preclinical model: Biomarker of long-term drug efficacy

Pokorna, Katerina, Le Pogam, Carole, Chopin, Martine, Balitrand, Nicole, Reboul, Murielle, Cassinat, Bruno, Chomienne, Christine, Padua, Rose Ann, Pla, Marika

Journal:

Molecular and Cellular Probes

Year:

2013

Language:

english

File:

PDF, 386 KB

english, 2013

37

Application of the Phosphoramidate ProTide Approach to 4‘-Azidouridine Confers Sub-micromolar Potency versus Hepatitis C Virus on an Inactive Nucleoside

Perrone, Plinio, Luoni, Giovanna M., Kelleher, Mary Rose, Daverio, Felice, Angell, Annette, Mulready, Sinead, Congiatu, Costantino, Rajyaguru, Sonal, Martin, Joseph A., Levêque, Vincent, Le Pogam, Sop

Journal:

Journal of Medicinal Chemistry

Year:

2007

Language:

english

File:

PDF, 167 KB

english, 2007

38

The Design, Synthesis, and Antiviral Activity of 4′-Azidocytidine Analogues against Hepatitis C Virus Replication: The Discovery of 4′-Azidoarabinocytidine

Smith, David B., Kalayanov, Genadiy, Sund, Christian, Winqvist, Anna, Pinho, Pedro, Maltseva, Tatiana, Morisson, Veronique, Leveque, Vincent, Rajyaguru, Sonal, Pogam, Sophie Le, Najera, Isabel, Benkes

Journal:

Journal of Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 114 KB

english, 2009

39

The Design, Synthesis, and Antiviral Activity of Monofluoro and Difluoro Analogues of 4′-Azidocytidine against Hepatitis C Virus Replication: The Discovery of 4′-Azido-2′-deoxy-2′-fluorocytidine and 4′-Azido-2′-dideoxy-2′,2′-difluorocytidine

Smith, David B., Kalayanov, Genadiy, Sund, Christian, Winqvist, Anna, Maltseva, Tatiana, Leveque, Vincent J.-P., Rajyaguru, Sonal, Pogam, Sophie Le, Najera, Isabel, Benkestock, Kurt, Zhou, Xiao-Xiong,

Journal:

Journal of Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 164 KB

english, 2009

40

Randomized Controlled Trial of Danoprevir Plus Peginterferon Alfa-2a and Ribavirin in Treatment-Naïve Patients With Hepatitis C Virus Genotype 1 Infection

Marcellin, Patrick, Cooper, Curtis, Balart, Luis, Larrey, Dominique, Box, Terry, Yoshida, Eric, Lawitz, Eric, Buggisch, Peter, Ferenci, Peter, Weltman, Martin, Labriola–Tompkins, Emily, Le Pogam, Soph

Journal:

Gastroenterology

Year:

2013

Language:

english

File:

PDF, 517 KB

english, 2013

41

Discovery of a Novel Series of Potent Non-Nucleoside Inhibitors of Hepatitis C Virus NS5B

Schoenfeld, Ryan C., Bourdet, David L., Brameld, Ken A., Chin, Elbert, de Vicente, Javier, Fung, Amy, Harris, Seth F., Lee, Eun K., Le Pogam, Sophie, Leveque, Vincent, Li, Jim, Lui, Alfred S.-T., Naje

Journal:

Journal of Medicinal Chemistry

Year:

2013

Language:

english

File:

PDF, 2.12 MB

english, 2013

42

BCL-2 inhibition with ABT-737 prolongs survival in an NRAS/BCL-2 mouse model of AML by targeting primitive LSK and progenitor cells

Beurlet, S., Omidvar, N., Gorombei, P., Krief, P., Le Pogam, C., Setterblad, N., de la Grange, P., Leboeuf, C., Janin, A., Noguera, M.-E., Hervatin, F., Sarda-Mantel, L., Konopleva, M., Andreeff, M.,

Journal:

Year:

2013

Language:

english

File:

PDF, 2.44 MB

english, 2013

43

In Vivo Emergence of a Novel Mutant L159F/L320F in the NS5B Polymerase Confers Low-Level Resistance to the HCV Polymerase Inhibitors Mericitabine and Sofosbuvir

Tong, X., Le Pogam, S., Li, L., Haines, K., Piso, K., Baronas, V., Yan, J.-M., So, S.-S., Klumpp, K., Najera, I.

Journal:

The Journal of Infectious Diseases

Year:

2014

Language:

english

File:

PDF, 308 KB

english, 2014

44

Évaluation des pratiques professionnelles en urologie à partir du Dossier médical informatisé de spécialité : surveillance d’indicateurs de qualité des biopsies prostatiques par maîtrise statistique des processus

Le Pogam, M.-A., Perrin, P., Paparel, P., Touzet, S., Colin, C.

Journal:

Revue d'Épidémiologie et de Santé Publique

Year:

2008

Language:

french

File:

PDF, 95 KB

french, 2008

45

1177 RAPID AND SUSTAINED ACHIEVEMENT OF UNDETECTABLE HCV RNA DURING TREATMENT WITH RITONAVIR-BOOSTED DANOPREVIR/PEG-IFNa-2A/RBV IN HCV GENOTYPE 1 OR 4 PATIENTS: DAUPHINE WEEK 12 INTERIM ANALYSIS

Everson, G., Cooper, C., Hezode, C., Shiffman, M.L., Yoshida, E., Beltran-Jaramillo, T., Ferenci, P., Zeuzem, S., Brunda, M., Shulman, N., Navarro, M., Voulgari, A., Najera, I., Le Pogam, S., Yetzer,

Journal:

Journal of Hepatology

Year:

2012

Language:

english

File:

PDF, 58 KB

english, 2012

46

Impact of Scedosporium apiospermum complex seroprevalence in patients with cystic fibrosis

Parize, Perrine, Billaud, Sandrine, Bienvenu, Anne L., Bourdy, Stéphanie, le Pogam, Marie A., Reix, Philippe, Picot, Stéphane, Robert, Raymond, Lortholary, Olivier, Bouchara, Jean-Philippe, Durieu, Is

Journal:

Journal of Cystic Fibrosis

Year:

2014

Language:

english

File:

PDF, 339 KB

english, 2014

47

A COLD NOVEMBER.

Le Pogam, Adrien, Lamare, Frederic, Hatt, Mathieu, Fernandez, Philippe, Le Rest, Catherine Cheze, Visvikis, Dimitris

Journal:

Year:

1910

Language:

english

File:

PDF, 173 KB

english, 1910

48

MRI data driven partial volume effects correction in PET imaging using 3D local multi-resolution analysis

Le Pogam, Adrien, Lamare, Frederic, Hatt, Mathieu, Fernandez, Philippe, Le Rest, Catherine Cheze, Visvikis, Dimitris

Journal:

Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment

Year:

2013

Language:

english

File:

PDF, 417 KB

english, 2013

49

EPPING BUTTER.

Le Pogam, Carole, Krief, Patricia, Beurlet, Stephanie, Soulié, Annie, Balitrand, Nicole, Cassinat, Bruno, Cavé, Helene, Kosmider, Olivier, Setterblad, Niclas, Leboeuf, Christophe, Sarda-Mantel, Laure,

Journal:

Year:

1853

Language:

english

File:

PDF, 384 KB

english, 1853

50

Localization of the NRAS:BCL-2 complex determines anti-apoptotic features associated with progressive disease in myelodysplastic syndromes

Le Pogam, Carole, Krief, Patricia, Beurlet, Stephanie, Soulié, Annie, Balitrand, Nicole, Cassinat, Bruno, Cavé, Helene, Kosmider, Olivier, Setterblad, Niclas, Leboeuf, Christophe, Sarda-Mantel, Laure,

Journal:

Leukemia Research

Year:

2013

Language:

english

File:

PDF, 1.03 MB

english, 2013

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